Center for Platelet Function Studies



Mark I. Furman, MD

Past Research Funding

Platelet Function in Coronary Artery Disease, Scientific Council, University of Massachusetts Medical School, Principal Investigator, 7/1/94-6/30/99 $97,000 Direct costs

A Phase II, Placebo-controlled, Multicenter Study of TLC C-53 as an Adjunct to Thrombolytic Therapy in Patients with Acute Myocardial Infarction. Liposomal Intervention Followed by Thrombolysis (LIFT). The Liposome Company, 8/1/95-12/1/96, Principal Investigator, $88,000 Direct costs

The Effects of TLC C-53 on Platelet and Leukocyte Function in Patients Receiving Thrombolytic Therapy for Acute Myocardial Infarction. The Liposome Company, 8/1/95-12/1/96, Principal Investigator, $34,000 Direct costs

Antiplatelet Therapy or Lovenox Plus Antiplatelet Therapy for Patients with an Increased Risk of Stent Thrombosis. Rhone Poulec Rorer, 4/1/95-12/1/96, Principal Investigator, $40,800 Direct Costs

Platelet Function in Congestive Heart Failure Scientific Council, University of Massachusetts Medical School, Principal Investigator, 7/1/95-6/30/96 $10,000 Direct costs

Diagnosis of Acute Myocardial Infarction by P-Selectin Profile and its Diagnostic Value in Acute Coronary Syndromes. Centocor Diagnostics of PA, Inc., 11/97-9/98, Co-Principal Investigator, $112,500 Direct Costs

Diagnosis of Acute Myocardial Infarction by Measurement of Circulating Monocyte-Platelet Aggregates. CompuCyte Corp., 11/97-9/98, Principal Investigator, $43,750 Direct Costs

Prediction of Cardiac Events after Percutaneous Coronary Intervention by Measurement of Circulating Monocyte-Platelet Aggregates CompuCyte Corp., 11/97-9/98, Principal Investigator, $37,500 Direct Costs

A Study to Assess the Equivalence of the Accumetrics Rapid Platelet Function Assay (RPFA) in Patients Who are Undergoing Coronary Intervention Procedures to a GPIIb-IIIa Receptor Blockade Assay Using I125 Abciximab. Accumetrics, Inc., 8/98-2/99, Co-Principal Investigator $73,000 Direct costs

The Effects of GPIIb-IIIa Antagonists on In-Vitro Platelet Procoagulant Activity and Leukocyte-Platelet Aggregation. Centocor, Inc., 2/98-1/99, Principal Investigator, $23,000 Direct costs.

Diagnosis of Acute Myocardial Infarction by Measurement of Circulating Monocyte-Platelet Aggregates (Phase II). CompuCyte Corp., Principal Investigator, 2/3/99-9/3/99 $168,874 Direct costs

Diagnosis of Stroke by Measurement of Circulating Monocyte-Platelet Aggregates. CompuCyte Corp., Principal Investigator, 7/13/99-4/13/00 $57,624 Direct costs

The Effects of Retaplase and Alteplase on Platelet Function in Acute Myocardial Infarction, Centocor, Inc, Principal Investigator $143,466 Direct costs

In Vivo Effects of Abciximab on Platelet and Leukocyte Activation, Leukocyte-Platelet Aggregation, Platelet Procoagulant Activity, and Platelet-Derived Microparticles in Patients with Unstable Angina/Non-Q-Wave Myocardial Infarction: A Case-Control Study, Centocor, Inc, Principal Investigator, $155,456 Direct costs

In Vivo Effects of Abciximab on Platelet-Endothelial Cell Adhesion in Patients with Unstable Angina/Non-Q-Wave Myocardial Infarction: A Case-Control Study, Centocor, Inc, Principal Investigator, $32,378 Direct costs

A Blinded, Randomized Comparative Trial of Dalteparin versus Unfractionated Heparin in Conjunction with Abciximab Platelet GP IIb/IIIa Inhibition During and Following Elective Percutaneous Coronary Intervention (Platelet function core laboratory). Principal Investigator, Pharmacia & Upjohn, $56,905, Direct costs

Placebo Controlled Randomized Administration of Reduced Dose Abciximab Prior to Percutaneous Coronary Intervention in Patients Receiving Intravenous Abciximab Infusion Following Pharmacologic Reperfusion of Acute Myocardial Infarction. (Platelet function core laboratory). Principal Investigator, Centocor, Inc. $23,655 Direct costs

An Open Labelled, Randomized, Parallel, Dose-Finding (Dose-Ranging) Study of TNK-tPA in Combination with AGGRASTAT in the Treatment of Acute Myocardial Infarction (FASTER Trial). Principal Investigator, Merck, Inc. $57,168 Direct costs.

Assessment of Platelet Function in Subjects Receiving Clopidogrel or Ticlopidine Accumetrics Protocol # P95049. Principal Investigator, Accumetrics, Inc. $23,000 Direct costs

Assessment of Platelet Function in Subjects Receiving Eptifibatide Accumetrics Protocol # P95038. Principal Investigator, Accumetrics, Inc. $26,000 Direct costs